Whether you have just been diagnosed, you have been living with hereditary angioedema (HAE) for some time, or you have a family member or friend suffering from HAE, it is important to understand the disease and to be prepared.

HAE is a rare, serious and potentially life-threatening genetic disorder occurring in 1 out 50.000 people. In Europe approximately 10.000 people are affected.

HAE causes repeated episodes of spontaneous swelling that can occur at any time and in almost any part of the body but more predominantly in the hands, feet, face, airway (throat) and internal organs. HAE is not an allergy or allergic reaction. HAE is the result of a genetic mutation caused by a deficiency of the blood protein functional C1 esterase inhibitor (C1-INH).